Hippokratia 1999, 3(1): 17 - 22
As ischemic renal disease or ischemic nephropathy is defined renal failure due to significant obstruction to renal blood flow caused mainly by atherosclerotic renal artery disease. Ischemia, hypertention and atheroembolic disease seem to be the main pathogenetic mechanisms causing renal atrophy and leading patients with ischemic nephropathy to progressive renal failure.
Revascularization, in a fairly high proportion of patients, is not effective causing rather deterioration than improvement of renal function. The best results have been reported when revascularization is performed in patients with renal function in the "window" area of serum creatinine between 1,5 to 3 mg/dl.